Bacterial Control in Partial Thickness Burns Using Silver-containing Wound Dressings

Ghent University Hospital (UZ)

Status

Completed

Conditions

Burn Wounds - Partial Thickness (2nd Degree)

Treatments

Procedure: aquacel AG hydrofiber versus acticoat burn dressing

Study type

Interventional

Funder types

Other

Identifiers

2006/224

Details and patient eligibility

About

This study is to compare the treatment with two different silver-containing wound dressings: aquacel AG hydrofiber versus acticoat burn dressing.

Enrollment

100 patients

Sex

All

Ages

Under 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Burn wounds with flux values, measured by Laser Doppler Imaging, corresponding with expected healing time between 7 and 21 days, flux values between 200 and 1000 (red-pink or pink-yellow-green colour)
Wounds treated with a hydrocolloid paste prior to LDI
Possibility to follow the complete treatment schedule until wound healing and participation on complete follow-up schedule
Informed consent
Partial thickness burns with TBSE < 40%

Exclusion criteria

Mean flux values < 200 or > 1000
TBSA > 40%
Impossibility to debride necrotic skin prior to LDI measurement
Wounds treated with any topical ointments or dressings other than hydrocolloid prior to LDI
Not following the complete treatment schedule or missing some evaluations during the follow-up period
Patient has any condition that seriously compromises the patient's ability to complete the study
Patient has participated in another study using an investigational drug within the previous 30 days
Patient has one or more medical condition(s)that in the opinion of the investigator would make the patient an inappropriate candidate for this study
The plastic surgeon decides that surgery is necessary due to unusual circumstances
Patient wish to decline from the study
No informed consent
Full thickness burns