Bacterial Infections in Patients with Cirrhosis in Argentina: Clinical and Microbiological Characteristics

Hospital Italiano de Buenos Aires

Status: Completed

Conditions: Resistant Infection; Cirrhosis; Morality; Bacterial Infections

Treatments: Other: This is an observational study without intervention

Study type: Observational

Funder types: Other

Identifiers

NCT03919032

3879

Details and patient eligibility

About

In recent years, there has been an increasing prevalence of bacterial infections caused by multiresistant and extremely resistant organisms in patients with cirrhosis. These infections are associated with a worse prognosis, generate difficulties in the management of the patient during hospitalization and increase health costs.

The main objective of this project is to estimate the prevalence of infections by multiresistant bacteria in patients with cirrhosis. Additionally, the prevalence of other antibiotic resistance patterns and morbi-mortality in the study population will be evaluated.

For these purposes, a multicenter prospective cohort study will be carried out, including patients with cirrhosis who present bacterial infections at the time of admission, or during hospitalization.

Performing a study in Argentina on the clinical and microbiological characteristics of bacterial infections in patients with cirrhosis could be very useful to develop new strategies for prevention and treatment of this severe complication.

Enrollment: 472 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with cirrhosis
• Patients older than 17 years.
• Patients who are hospitalized for bacterial infections, or who develop bacterial infections while hospitalized

Exclusion criteria

• Refusal to participate in the informed consent process