Bacterial Reduction and Post Operative Endodontic-pain Using Different Kinematics

Ain Shams University

Status: Completed

Conditions: Root Canal Infection

Treatments: Other: root canal shaping

Study type: Interventional

Funder types: Other

Identifiers

NCT04990115

FDASU-RECD091615

Details and patient eligibility

About

This study was conducted to compare the antibacterial effect and degree of postoperative pain of single rotary and reciprocating file systems during endodontic therapy

Full description

Introduction: Instrumentation kinematic is one of the many aspects of shaping files that underwent heavy development through the last decade. The impact of the type of motion used to drive shaping instruments was heavily studied but mostly in-vitro. More randomized clinical trials are needed to achieve a reliable body of data concerning the issue.

Aim: This study aimed to evaluate the effect of varying shaping files' kinematics on bacterial reduction, post-operative pain and the incidence of flare-ups. Methods: Necrotic, asymptomatic, single-rooted mandibular premolars with single canals were used in the study, where 46 patients were randomly allocated to two groups. In the first group, WaveOne Gold was used for mechanical preparation while One Shape was used in the second group. Samples were taken preoperatively (S1) and after chemomechanical preparation (S2). Bacterial reduction was evaluated and compared between both groups via culturing technique and quantitative analysis by real-time polymerase chain reaction (qPCR). Post-operative pain and the incidence of flare-ups were also evaluated using the visual analog scale (VAS) method.

Enrollment: 50 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• mandibular premolars
• single rooted
• single canalled
• necrotic pulps
• asymptomatic apical periodontitis

Exclusion criteria

• gross caries
• root/crown fracture
• sinus tract
• swelling
• intake of antibiotics within previous 3 months
• pain with percussion

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups

rotation

Active Comparator group

Description:

root canal preparation performed using rotating instruments

Treatment:

Other: root canal shaping

reciprocation

Active Comparator group

Description:

root canal preparation performed using reciprocating instruments

Treatment:

Other: root canal shaping