Baduanjin Lower Elevated Blood PreSsure Study (BLESS)

National Center for Cardiovascular Diseases

Status: Completed

Conditions: Elevated Blood Pressure

Treatments: Behavioral: Brisk walking; Behavioral: Baduanjin

Study type: Interventional

Funder types: Other

Identifiers

NCT05397535

2022-1724

Details and patient eligibility

About

The aim of this study is to evaluate the effects of Baduanjin on blood pressure in individuals with high normal blood pressure (SBP 130-139 mmHg, and/or DBP 85-89 mmHg), as well as on glucose and lipid metabolism, quality of life, psychology, exercise, immune inflammation, endothelial function, and arterial stiffness.

Enrollment: 216 patients

Sex: All

Ages: 40+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 40 years or older;
• Systolic blood pressure (SBP) <140 mmHg and diastolic blood pressure (DBP) <90 mmHg
• SBP 130-139 mmHg, and/or DBP 85-89 mmHg

Exclusion criteria

• Diagnosis of hypertension (SBP≥140 mmHg, and/or DBP ≥90mmHg）
• History of cardiovascular diseases, such as coronary heart disease, heart failure, stroke, and peripheral vascular disease
• Diagnosis of chronic kidney disease, primary aldosteronism, Cushing's syndrome, or pheochromocytoma
• Newly diagnosed cancer or cancer metastasis within 5 years
• History of autoimmune disease
• Having taken antihypertensive drugs or immunoregulators within 2 weeks
• A long-term need for antihypertensive drugs or immunomoregulators
• Unable to maintain moderate intensity exercise due to illness or other reasons
• Pregnant, breastfeeding, or planning to become pregnant within the next 1 year
• Currently taking regular exercise (at least 30 minutes of moderate-intensity exercise at least three times a week)
• Allergic to sports bracelets
• Having participated or been participating in other clinical trials within the last 3 months
• Unable to use smartphones
• Other factors that may affect the follow-up, such as alcohol or substance abuse in the last 12 months, planing to live out of town for a long time, or diagnosis of dementia or cognitive impairment which indicates incapability of completing the study
• Unable to accurately measure blood pressure using the sphygmomanometer provided by the study due to a too large or too small arm circumference

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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216 participants in 3 patient groups

Self-directed exercise group

No Intervention group

Description:

Participants in the self-directed exercise group will choose the type and duration of exercise by their preference.

Brisk walking group

Active Comparator group

Description:

Participants in Brisk Walking Group will participate in brisk walking for 52 weeks (≥5 days/week, about 30 minutes/day).

Treatment:

Behavioral: Brisk walking

Baduanjin group

Experimental group

Description:

Participants in Baduanjin Group will practice Baduanjin singly for 52 weeks (≥5 days/week, about 30 minutes/day).

Treatment:

Behavioral: Baduanjin