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Baduanjin Sequential Therapy and Cardiac Function of AMI With Reduced EF After PCI (BST-AMI)

S

Shenyang Northern Hospital

Status

Unknown

Conditions

AMI

Treatments

Behavioral: Aerobic exercise
Behavioral: Baduanjin sequential therapy

Study type

Interventional

Funder types

Other

Identifiers

NCT05201274
BST-AMI

Details and patient eligibility

About

Acute myocardial infarction (AMI) is one of the leading causes of death around the world, with the potential for substantial morbidity and mortality. The increasing evidence indicates that exercise training has beneficial effects on LV remodelling in post-MI patients with greater benefits occurring when training earlier following MI, among which the earliest time for rehabilitation is one week after myocardial infarction. However, the effect of Baduanjin sequential therapy for patients after one week of AMI has yet to be assessed. Therefore, the aim of this study is to assess the impact of Baduanjin sequential therapy on cardiac and physical function in patients with AMI and reduced ejection fraction after primary PCI.

Enrollment

140 estimated patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Acute myocardial infarction undergoing primary percutaneous coronary intervention;
  • Aged 18 years or over and under 80 years;
  • 35% < LVEF < 50% and LV < 65mm;
  • With informed consents

Exclusion criteria

  • Severe symptomatic congestive heart failure (KILLIP cardiac function class III-IV);
  • Malignant arrhythmias (ventricular fibrillation, ventricular tachycardia, frequent multiple source ventricular premature);
  • Uncontrolled hypertension (systolic blood pressure greater than 160mmhg, diastolic blood pressure greater than 100mmhg);
  • Life-threatening diseases with limited life expectancy <6 months;
  • Inability or difficulty to exercise;
  • Participation in other clinical trials

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

140 participants in 2 patient groups

Baduanjin sequential therapy
Experimental group
Treatment:
Behavioral: Baduanjin sequential therapy
Aerobic exercise
Active Comparator group
Treatment:
Behavioral: Aerobic exercise

Trial contacts and locations

1

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Central trial contact

Yaling Han, MD; Meili Liu, MD

Data sourced from clinicaltrials.gov

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