Balanced Volume Replacement Therapy With Ringer's Acetate Solution in Burn Injury (VoLTRAB)

Klinikum St. Georg gGmbH

Status: Completed

Conditions: Severe Burn Injury

Study type: Observational

Funder types: Other

Identifiers

NCT00609700

EK-BR-35/07-1

Details and patient eligibility

About

This observational study compares the influence of Ringer's Lactate solution and Ringer's Acetate solution on organ function scores following severe burn injury.

Full description

In the early period following severe burn injury volume replacement with high amounts of crystalloids is necessary. In this study we compare the organ function scores of a historical patient group, treated with Ringer's Lactate solution, with an actual patient population, treated with Ringer's Acetate solution.

Enrollment: 82 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age >=18 years and <80years
• Burned surface area >20% and <70%
• Burn injury < 24 hours
• Agreement to the study procedures

Exclusion criteria

• Burned surface area > 70%
• Expected survival time < 24 hours
• Acute or chronic heart failure NYHA III or IV
• Adult respiratory distress syndrome
• Renal failure
• Hepatic failure

Trial design

82 participants in 2 patient groups

1

Description:

Historical group: patients treated with Ringer's Lactate solution after severe burn injury

2

Description:

Actual group: patients treated with Ringer's Acetate solution after severe burn injury