Bare Platinum Coils Versus Second-generation Hydrocoils

Seoul National University

Status: Terminated

Conditions: Intracranial Aneurysm; Aneurysm, Ruptured

Treatments: Device: Coil embolization

Study type: Interventional

Funder types: Other

Identifiers

NCT04988503

B-2012/652-002

Details and patient eligibility

About

Comparison of clinical and radiological outcomes between bare platinum coil group and second-generation hydrogel coils for treatment of ruptured intracranial aneurysms.

Full description

The investigators aimed to analyze whether the use of second-generation hydrogel coils for the treatment of ruptured intracranial aneurysms improves clinical and angiographic outcomes compared with the use of bare platinum coils.

Enrollment: 68 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 19 year old or older
• untreated ruptured intracranial aneurysms with an anatomy such that endovascular treatment with either bare platinum or second-generation hydrogel coils was considered feasible.
• person who agreed to study

Exclusion criteria

• contrast allgery (+)
• combined other intracranial lesions (tumor, moyamoya disease, cerebral vascular diseases)
• ineligible for coil embolization

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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68 participants in 2 patient groups

Second-generation hydrogel coil group

Experimental group

Description:

Treatment using second-generation hydrogel coils (had to constitute \> 50% of the total coil length) for ruptured cerebral aneurysms

Treatment:

Device: Coil embolization

Bare platinum coil group

Active Comparator group

Description:

Treatment using bare metal coil only for ruptured cerebral aneurysms

Treatment:

Device: Coil embolization