Bariatric Surgery and Skeletal Health

Mass General Brigham

Status: Completed

Conditions: Morbid Obesity

Study type: Observational

Funder types: Other

Identifiers

NCT01098942

2009P001445

Details and patient eligibility

About

Bone loss may occur after bariatric (weight loss) surgery, but standard methods of measuring bone density in obese patients are potentially inaccurate. This study uses quantitative computed tomography to examine changes in bone mineral density after bariatric surgery. We are also studying mechanisms which may explain bone loss after bariatric surgery.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Either scheduled for Roux-en-Y Gastric Bypass surgery or enrolled in a lifestyle weight management program

Exclusion criteria

• Weight ≥ than 450 lbs
• Postmenopausal women
• Significant heart, kidney, liver, or malignant disease
• Current disorders known to affect bone
• Use of medications known to affect bone for more than 7 days in the past 12 months

Trial design

50 participants in 2 patient groups

Surgical

Description:

Roux-en-Y gastric bypass surgery

Non-surgical

Description:

Non-surgical lifestyle weight management