Baseline Cardiovascular Measurements in Pediatric Spinal Cord Injury

Shriners Hospitals for Children

Status: Completed

Conditions: Spinal Cord Injury

Study type: Observational

Funder types: Other

Identifiers

NCT01599455

SHC-SCI-CV

Details and patient eligibility

About

Following spinal cord injury (SCI), the body loses normal control of blood pressure and heart rate, and there is a risk of sudden and dangerous increases in blood pressure, namely, autonomic dysreflexia (AD). It is important to be aware of baseline blood pressures and heart rates in individuals in order to detect AD. However, baseline values vary in developing children, and may be more variable in children with SCI. Thus, the objective of this study is to determine baseline blood pressure and heart rate measurements in children with SCI during rest and during urodynamic testing.

The investigators hypothesize that 1) blood pressures will increase with increasing age and body mass index; 2) heart rate will decrease with increasing age; 3) blood pressures will increase with increase in bladder filling; 4) blood pressures will increase will increase with increasing duration of injury.

Enrollment: 146 patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children and adolescents with spinal cord injury
• age 18 years or younger

Exclusion criteria

• known history of hypertension, cardiac, renal, or thyroid disease
• recent surgical procedure less than 2 weeks prior to admission or visit
• fever or signs of active infection or inflammation

Trial design

146 participants in 3 patient groups

Inpatient

Description:

Youths admitted for inpatient rehabilitation training

Outpatient

Description:

Youths visiting outpatient clinics

Urodynamic study

Description:

Youths who undergo scheduled urodynamic study