Bathing Additives in Pediatric Atopic Dermatitis

Mayo Clinic

Status: Terminated

Conditions: Dermatitis, Atopic

Treatments: Other: Bathing Additive

Study type: Interventional

Funder types: Other

Identifiers

NCT02582788

15-003161

Details and patient eligibility

About

The current clinical guidelines for management of atopic dermatitis now recommend bleach baths. This requires simply the addition of regular household bleach to twice-weekly baths. At the Mayo Clinic, dilute acetic acid (vinegar) has been recommended for decades in wet wraps to treat patients hospitalized for their atopic dermatitis. However, this practice has not been widely adopted in the pediatric dermatology community. Will the use of dilute acetic acid (vinegar) in twice weekly baths help manage atopic dermatitis in pediatric patients as well as, or better than, the current accepted guidelines?

Enrollment: 10 patients

Sex: All

Ages: 6 months to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients from 6 months to 17 years of age

2. Currently residing in US.

3. Follow up visits at 1 month, 3 months and 6 months after initiation of treatment in study (Figure 1).

4. Last follow-up at 1 year in clinic or via written mailed-out survey.

5. Diagnosis of atopic dermatitis AND

   1. Have active signs of bacterial skin infection OR
   2. Any documented suspected history of bacterial skin infection (weeping, crusting, and/or pustules on exam), OR
   3. Prescription for oral antibiotics for skin infection in the past 6 months from any provider). OR
   4. Have been prescribed bleach baths as part of an atopic dermatitis skin care regimen.

Exclusion criteria

1. Superficial skin infection without diagnosis of atopic dermatitis
2. Lack of in-clinic follow up assessment at 6 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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10 participants in 2 patient groups

Bleach

Active Comparator group

Description:

Patients will use bleach added to their baths twice a week.

Treatment:

Other: Bathing Additive

Vinegar

Active Comparator group

Description:

Patients will use vinegar (dilute acetic acid) added to their baths twice a week.

Treatment:

Other: Bathing Additive