Be-HealthY: Behavioral Risk Factors for Poor Vascular Health in Youth

Johns Hopkins University

Status: Completed

Conditions: Hypertension; Prehypertension; Endothelial Dysfunction; Vascular Stiffness; Elevated Blood Pressure; Overweight and Obesity; Sleep

Treatments: Diagnostic Test: Emotional/Behavioral Assessments; Diagnostic Test: Laboratory assessments; Diagnostic Test: Cardiovascular Assessments; Diagnostic Test: Actigraphy

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT03934398

1R56HL139620 (U.S. NIH Grant/Contract)

IRB00196923

Details and patient eligibility

About

The investigators aim to determine the association of dietary intake on cardiovascular disease risk factors among children with overweight and obesity who are being evaluated for elevated blood pressure.

The investigators will also investigate for predictors of vascular function and determine if predictors vary by level of sodium intake.

Full description

This research is being done to determine if the food or salt eaten can cause arteries to be stiffer and/or not work as well and if it can impact blood pressure over a 24-hour period of time. The investigators also want to determine if there are any risk factors or blood tests that can predict how stiff arteries are or how well arteries function. The investigators hope that the information from this study will help the investigators prevent blood pressure-related cardiovascular disease in children. This knowledge could help shape future guidelines on how to best prevent and treat high blood pressure and heart disease in children.

Enrollment: 41 patients

Sex: All

Ages: Under 22 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Overweight or obese
• Elevated blood pressure
• Referred to the ReNEW Clinic at Johns Hopkins University for evaluation and treatment of elevated blood pressure.

Exclusion criteria

• The only children who will not be eligible for inclusion in this study are those who are non-English speaking.

Trial design

41 participants in 1 patient group

ReNEW Clinical Cohort

Description:

Individuals evaluated in the ReNEW Clinic at Johns Hopkins University who join the ReNEW Clinic Cohort Study are eligible for this cross-sectional study. Tests will be done for all participants which includes Cardiovascular Assessments, Actigraphy and Laboratory assessments.

Treatment:

Diagnostic Test: Actigraphy

Diagnostic Test: Cardiovascular Assessments

Diagnostic Test: Laboratory assessments

Diagnostic Test: Emotional/Behavioral Assessments