BEACON Care ® System Assisting Ventilation in Pressure Support Ventilation (PSV) Patient (BEACON3)

Università degli Studi di Ferrara

Status: Completed

Conditions: Artificial Respiration

Treatments: Device: Pressure Support Over Support; Device: Pressure Support Under Support; Device: PEEP Under Level; Device: PEEP Over Level

Study type: Interventional

Funder types: Other

Identifiers

NCT02760147

20150604

Details and patient eligibility

About

The aim of this study is to evaluate the ventilator settings advice given by the BEACON care system in fitting with best level of support in patient under mechanical ventilation in Pressure Support mode.

Full description

The purpose of this study is to evaluate whether pressure support settings suggested by the B3 system and pressure support as well as Positive End Expiratory Pressure (PEEP) settings suggested by the B5 system, i.e. balancing under and over support based upon physiological models and simple clinical measures, are consistent with keeping patients within appropriate levels of support as assessed by the ratio between airwaiy pressure generated by the respiratory muscles (Pmus) and the maximum inspiratory pressure (MIP) (Pmus/MIP), the ratio between the inspiratory time (TI) and total respiratory time (TTOT) (TI/TTOT) and the Tension-Time index (TTi), these being obtained using less frequently used esophageal catheter measurements.

Enrollment: 85 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Under mechanical ventilation in Pressure Support mode

Exclusion criteria

• Neuromuscular impairment

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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85 participants in 4 patient groups

Pressure Support Over Support

Other group

Description:

Pressure Support Level upward by 50%, 2 hours

Treatment:

Device: Pressure Support Under Support

Device: Pressure Support Over Support

Pressure Support Under Support

Other group

Description:

Pressure Support Level downward by 50%, 2 hours

Treatment:

Device: Pressure Support Under Support

Device: Pressure Support Over Support

PEEP Over Level

Other group

Description:

PEEP Level upward by 50%, 2 hours

Treatment:

Device: PEEP Over Level

Device: PEEP Under Level

PEEP Under Level

Other group

Description:

PEEP Level downward by 50%, 2 hours

Treatment:

Device: PEEP Over Level

Device: PEEP Under Level