Beat Childhood Cancer Specimen Banking and Data Registry

Giselle Sholler

Status: Enrolling

Conditions: Pediatric Cancer

Treatments: Other: No intervention- registry only

Study type: Observational

Funder types: Other

Identifiers

NCT04715178

BCC-BIO-001

Details and patient eligibility

About

This is an observational data registry study of pediatric cancer patients at participating Beat Childhood Cancer Consortium sites involving specimen banking and data collection.

Full description

This observational registry and banking study is being performed on a large cohort of patients who have been identified to receive molecular testing to better understand the relationship between genomic and molecular information and clinical outcomes, enabling timely and informed treatment decisions by physicians for cancer patients. We hypothesize that large gene panels, sequencing (DNA/RNA), and epigenetics of tumors can identify molecular aberrations in tumors that can be leveraged to offer more effective treatment. Findings may suggest additional research will be required to better understand the molecular underpinnings of the relationship between molecular abnormalities and disease. Banked specimens and the creation of tumor cell lines and xenograft models will enable this research to be performed.

Enrollment: 500 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• No age restrictions
• Patients with suspected or confirmed pediatric tumors
• Subject or his/her legally authorized representative (where applicable) signs the study consent.

Exclusion criteria

• Patient or his/her legally authorized representative (where applicable) did not consent for specimen banking and data collection for this study.

Trial design

500 participants in 1 patient group

Patients with suspected or confirmed pediatric solid tumors

Description:

Patients with suspected or confirmed pediatric solid tumors

Treatment:

Other: No intervention- registry only