Beat Childhood Cancer Specimen Banking and Data Registry

Giselle Sholler

Status

Enrolling

Conditions

Survivorship

Pediatric Cancer

Treatments

Other: No intervention- registry only

Study type

Observational

Funder types

Other

Identifiers

NCT04715178

BCC-BIO-001

Details and patient eligibility

About

This is an observational data registry study of pediatric cancer patients at participating Beat Childhood Cancer Consortium sites involving specimen banking and data collection.

Full description

This observational registry and banking study is being performed on a large cohort of subjects who have received molecular testing to better understand the relationship between genomic and molecular information and clinical outcomes, and to enable timely and informed treatment decisions by physicians for their cancers. We hypothesize that large gene panels, sequencing (DNA/RNA), and epigenetics of tumors can identify molecular aberrations that can be leveraged to offer more effective treatment. Findings may highlight additional areas of research required to better understand the molecular underpinnings of the relationship between molecular abnormalities and disease. Banked specimens and the creation of tumor cell lines and xenograft models will facilitate further advancement of this research.

Enrollment

1,000 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

No age restrictions
Subjects that fit into one of the following categories:
1. Subjects with suspected or confirmed cancers of childhood, adolescence, or young adulthood.
2. Survivors of a cancer of childhood, adolescence, or young adulthood (> 6 months off last therapy for cancer)
3. Subjects with a disease-matched condition
4. Healthy volunteers- including any participants with medical conditions that are not disease-matched.
Written informed consent in accordance with institutional and FDA guidelines must be obtained from all subjects (or subjects' legal representative).