Bedside Ultrasound Assessment of Gastric Content and Volume

University Health Network, Toronto

Status: Completed

Conditions: Gastroscopy

Treatments: Other: Ultrasound examination followed by ingestion of Apple Juice prior to a second ultrasound procedure, followed by gastroscopic suctioning of stomach content.

Study type: Interventional

Funder types: Other

Identifiers

NCT01151228

09-0764-BE

Details and patient eligibility

About

Patients undergoing gastroscopy will undergo two pre-procedure ultrasound scans of the stomach, once on arrival in the unit and on an empty stomach and a second time after consumption of a randomized amount of apple juice (0, 50, 100, 200, 300 or 400 mL). Immediately after ingestion and the second ultrasound scan, subjects will have their gastroscopy which will start by suctioning out the apple juice. Measurements of stomach fluid volume conducted by ultrasound will be compared to the actual volume removed during the gastroscopy procedure.

Enrollment: 108 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-80 years
• Weight 50-100 kg
• height greater than 150 cm
• ability to provide informed consent

Exclusion criteria

• recent upper GI bleed (within 1 month)
• previous lower esophageal or gastric surgery
• not fasted for 8 hours

Trial design

108 participants in 6 patient groups, including a placebo group

Zero volume

Placebo Comparator group

Description:

Patients will not ingest any apple juice prior to the second ultrasound.

Treatment:

Other: Ultrasound examination followed by ingestion of Apple Juice prior to a second ultrasound procedure, followed by gastroscopic suctioning of stomach content.

50 mL

Experimental group

Description:

Patients will ingest 50 mL apple juice prior to the second ultrasound.

Treatment:

Other: Ultrasound examination followed by ingestion of Apple Juice prior to a second ultrasound procedure, followed by gastroscopic suctioning of stomach content.

100 mL

Experimental group

Description:

Patients will ingest 100 mL apple juice prior to the second ultrasound.

Treatment:

Other: Ultrasound examination followed by ingestion of Apple Juice prior to a second ultrasound procedure, followed by gastroscopic suctioning of stomach content.

200 mL

Experimental group

Description:

Patients will ingest 100 mL apple juice prior to the second ultrasound.

Treatment:

Other: Ultrasound examination followed by ingestion of Apple Juice prior to a second ultrasound procedure, followed by gastroscopic suctioning of stomach content.

300 mL

Experimental group

Description:

Patients will ingest 300 mL apple juice prior to the second ultrasound.

Treatment:

Other: Ultrasound examination followed by ingestion of Apple Juice prior to a second ultrasound procedure, followed by gastroscopic suctioning of stomach content.

400 mL

Experimental group

Description:

Patients will ingest 400 mL apple juice prior to the second ultrasound.

Treatment:

Other: Ultrasound examination followed by ingestion of Apple Juice prior to a second ultrasound procedure, followed by gastroscopic suctioning of stomach content.