Beetroot Enriched Bread, Blood Pressure and Vascular Function

University of Reading

Status: Completed

Conditions: Hypertension

Treatments: Dietary Supplement: Bread

Study type: Interventional

Funder types: Other

Identifiers

NCT01706718

10/18

University of Reading (Other Identifier)

Details and patient eligibility

About

Dietary nitrate is known to lower blood pressure. Beetroot is a rich source of nitrate and could therefore be an important dietary component in the management of hypertension and cardiovascular disease, however consumption is relatively low. We evaluated the effects of beetroot enriched bread ingestion on acute microvascular reactivity, arterial stiffness and blood pressure response in healthy men.

Enrollment: 24 patients

Sex: Male

Ages: 18 to 64 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male
• A signed consent form
• Age 18-64 years
• Body mass index - 18.5-30 kg/m2
• Non-smoking, healthy individuals
• Normal blood pressure at screening (< 150/90)

Exclusion criteria

• Subjects with anaemia
• Sufferers of chronic illnesses
• Individuals with food allergies
• People with diabetes
• People with coeliac disease
• Women
• Vegetarians

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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24 participants in 2 patient groups, including a placebo group

Control white bread

Placebo Comparator group

Treatment:

Dietary Supplement: Bread

Beetroot bread

Experimental group

Treatment:

Dietary Supplement: Bread