Behavioral Activation for the Prevention and Treatment of Depression in Older Adults in a Municipal Context (DePrevent)

Sormland County Council, Sweden

Status: Enrolling

Conditions: Depressive Symptoms; Depression

Treatments: Behavioral: Brief Behavioral Activation; Other: Care as Usual

Study type: Interventional

Funder types: Other

Identifiers

NCT06415838

DePrevent

Details and patient eligibility

About

The goal of this randomized clinical trial is to investigate if a brief psychological treatment called Behavioral Activation (BA) works to prevent and treat depression in older adults in a municipal context in Sweden. It will also learn about the patients' and therapists' experiences of the BA-treatment.

The main questions it aims to answer are if the BA-treatment has an effect on the short and long term on:

• Depressive symptoms
• Anxiety symptoms
• Self-rated activation
• Functional ability
• Loneliness
• Self efficacy
• Mental wellbeing
• Quality of life
• Need for community care services

All participants will continue their care as usual (CAU), and half of the participants will be randomized to receive a five-session BA-treatment spread over two months as an add-on to CAU. All participants will answer a questionnaire in the beginning of the study, after two months, and after 3-, 6- and 12 months.

Full description

One third of the Swedish population aged 70 years and above report depressive symptoms, and between 5 - 15% have a major depressive disorder. Depression in older adults reduces quality of life and functional ability, and is associated with an increased risk for morbidity and mortality. Psychological treatment is considered a first-line treatment for depression, but is currently only offered to about 3% of older adults with depression in Sweden. A majority of older adults suffering from depression in Sweden are likely not to be identified and diagnosed, and thereby not treated for their depression. Furthermore, many older adults receive municipal care, and psychological treatment is currently not available in this context.

The goal of this randomized clinical trial is to investigate if a brief psychological treatment called Behavioral Activation (BA) works to prevent and treat depression in older adults in a municipal context in Sweden. It will also learn about the patients' and therapists' experiences of the BA-treatment. The therapists in the trial are social workers working in Eskilstuna municipality in Sweden.

All participants will continue their care as usual (CAU), and half of the participants will be randomized to receive a five-session BA-treatment spread over two months as an add-on to CAU. The BA-treatment will be delivered in the participants' home. All participants will answer a questionnaire in the beginning of the study, after two months, and after 3-, 6- and 12 months.

The main questions that the trial aims to answer are if the BA-treatment has an effect on the short and long term on:

• Depressive symptoms
• Anxiety symptoms
• Self-rated activation
• Functional ability
• Loneliness
• Self efficacy
• Mental wellbeing
• Quality of life
• Need for community care services

Enrollment: 160 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 65 years or older
• 5 points or above on the Geriatric Depression Scale 15, GDS-15
• Fluent in written and spoken Swedish
• Consents to participate in the trial

Exclusion criteria

• Not able to use the patient materials due to visual impairment
• Not able to communicate with therapist due to hearing impairment
• Diagnosis of major neurocognitive disorder
• Below 25 points on the Mini Mental State Examination, MMSE
• Elevated suicide risk
• Current substance- or alcohol use disorder
• Previous or current psychotic disorder
• Previous or current bipolar disorder
• Ongoing psychological treatment/pscyhotherapy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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160 participants in 2 patient groups

Brief Behavioral Activation plus Care as Usual

Experimental group

Description:

Five-session Brief Behavioral Activation intervention. Sessions 1 - 4 are completed once a week, and session 5 is a booster-session completed four weeks after session 4.

Treatment:

Other: Care as Usual

Behavioral: Brief Behavioral Activation

Care as Usual

Active Comparator group

Description:

Care as usual as provided by primary care and/or municipal care.

Treatment:

Other: Care as Usual