Behavioral Alcohol Responses (BAR) Study

Carnegie Mellon University

Status and phase: Active, not recruiting; Early Phase 1

Conditions: Alcoholism; Alcohol; Harmful Use; Alcohol Intoxication; Binge Drinking; Alcohol Use Disorder; Alcohol Drinking

Treatments: Other: Placebo; Drug: Alcohol

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT03467191

STUDY2017_00000346

R01AA025936 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study aims to identify risk factors that prospectively predict alcohol problems in young adults.

Full description

The vast majority of alcohol use takes place in social settings, yet nearly all human experimental work has administered alcohol to individuals in isolation. This study will examine the effects of alcohol in social groups and test whether these responses predict the escalation of alcohol use and development of alcohol use disorder symptoms. Participants will also complete smartphone surveys querying subjective responses to alcohol in their daily lives.

N=400 male and female young adults will participate in a laboratory session with two other participants and will consume either a moderate dose of alcohol or placebo beverage. Subjective and objective responses to alcohol will be assessed. Participants will also complete surveys on their smartphones; these will occur during drinking episodes and at random times throughout the day. Follow-up sessions will occur at 6-months and 12-months, to collect information about drinking habits and potential alcohol-related problems.

Enrollment: 782 patients

Sex: All

Ages: 21 to 29 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 21 to 29 years of age
• currently drinks alcohol
• owns a smartphone

Exclusion criteria

[Exclusion criteria are masked from public viewing until data collection is complete. Please contact project managers.]

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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782 participants in 2 patient groups, including a placebo group

Alcohol Beverage

Experimental group

Description:

Moderate dose of alcohol (target BAC .08%)

Treatment:

Drug: Alcohol

Placebo Beverage

Placebo Comparator group

Treatment:

Other: Placebo