Behavioral Dynamics Between Infants With Visual Loss and Healthy Controls

Sun Yat-sen University logo

Sun Yat-sen University

Status

Completed

Conditions

Behavioral Dynamics
Visual Impairment

Treatments

Other: Standardized video recording for behaviors

Study type

Observational

Funder types

Other

Identifiers

NCT03431207
CCPMOH2018-China-1

Details and patient eligibility

About

An individual senses the world and reflects feedbacks via independent behaviors. Such precise collaboration of the sensory and behavioral systems is fundamental to survival and evolution. When a sensory modality is altered, the behavioral system has the potential to fit in a substitute modality. However, the specific dynamics of human behaviors in response to sensory loss remain largely unknown due to the paucities of representative situations and large-scale samples. Here, the investigators focused on thousands of human infants who suffered varying degrees of visual stimuli deficiency in early stages, while their behavioral systems remained sensitive and thus retained high behavioral plasticity. Having access to this unique population provides an unprecedented opportunity to investigate the effect of diverse visual conditions on the behavioral system.

Enrollment

4,196 patients

Sex

All

Ages

Under 3 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Younger than 3 years of age

Exclusion criteria

Any brain and mental illnesses, or other known illnesses that may affect the behavioral patterns

Trial design

4,196 participants in 3 patient groups

healthy group
Description:
For the "healthy" group, the visual acuity of both eyes was in the 95% referenced range with no structural abnormalities. The referenced range could be found in the following publication: Mayer, DL., et al. Monocular acuity norms for the Teller Acuity Cards between ages one month and four years. Investigative Ophthalmology & Visual Science. 36(3):671 (1995)
Treatment:
Other: Standardized video recording for behaviors
mildly impaired group
Description:
The "mildly impaired" group was defined as a VA out of the 95% reference range in at least 1 eye, but the VA of both eyes was in the 99% referenced range with structural abnormalities.
Treatment:
Other: Standardized video recording for behaviors
severely impaired group
Description:
For the "severely impaired" group, the VA of both eyes was out of the 99% referenced range or worse than light perception with structural abnormalities.
Treatment:
Other: Standardized video recording for behaviors

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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