Behavioral Signs of Consciousness Recovery in Patients With Disorders of Consciousness (DOCSIGNS)

Hospitales Nisa

Status: Completed

Conditions: Brain Injuries; Consciousness Disorder

Treatments: Behavioral: Rehabilitation

Study type: Observational

Funder types: Other

Identifiers

NCT04687397

HN19025C73

Details and patient eligibility

About

Precise description of behavioral signs denoting transition from unresponsive wakefulness syndrome/vegetative state (UWS/VS) to minimally conscious state (MCS) or emergence from MCS after severe brain injury is crucial for prognostic purposes. A few studies have attempted this goal but involved either non-standardized instruments, limited temporal accuracy or samples, or focused on (sub)acute patients. The objective of this study is to describe the behavioral signs that led to a change of diagnosis, as well as the factors influencing this transition, in a large sample of patients with chronic disorders of consciousness after severe brain injury.

Enrollment: 100 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• documented medical diagnosis of CRS-R-based diagnosis of UWS or MCS at admission to the neurorehabilitation program

Exclusion criteria

• none

Trial design

100 participants in 1 patient group

Disorders of consciousness

Description:

Patients diagnosed as either in a Vegetative State or in a Minimally Conscious State

Treatment:

Behavioral: Rehabilitation