Belgian Screening Project for the Detection of Anderson-Fabry Disease in Hypertrophic Cardiomyopathy

Ghent University Hospital (UZ)

Status: Completed

Conditions: Left Ventricular Hypertrophy

Treatments: Other: blood sampling

Study type: Observational

Funder types: Other

Identifiers

NCT01198899

2009/035

Details and patient eligibility

About

The purpose of this study is to determine the prevalence of Fabry mutations in patients with left ventricular hypertrophy (moderate to severe), as measured by echocardiography.This study is a screening study

Enrollment: 540 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• All patients over 18 years undergoing a routine echocardiography in the participating hospitals
• Both genders will be considered.
• Patients can be included if on 2D echocardiography the maximal septal wall thickness > 13 mm and/or the posterior wall thickness > 13 mm. The limit for inclusion is kept relatively low to detect early forms of Fabry cardiomyopathy.

Trial design

540 participants in 1 patient group

left ventricular hypertrophy

Description:

Patients with left ventricular hypertrophy will be used.

Treatment:

Other: blood sampling