Benefit of Ethanol Sclerotherapy of Endometriomas Before Ovarian Stimulation on Pregnancy Rates in IVF/ICSI (SCLERENDO)

Poissy-Saint Germain Hospital

Status

Not yet enrolling

Conditions

Infertile Women Undergoing IVF or ICSI

Treatments

Procedure: ethanol sclerotherapy

Study type

Interventional

Funder types

Other

Identifiers

NCT06878053

2024-A02459-38

Details and patient eligibility

About

Evaluation of progressive pregnancy rates (with an embryo with cardiac activity at 12 weeks), on a first attempt at IVF/ICSI (fresh and frozen embryo transfers) following the discovery of one or two endometrioma(s) of 30 to 80 mm, without a history of cystectomy, and comparison between the two groups: ethanol sclerotherapy and therapeutic abstention

Enrollment

174 estimated patients

Sex

Female

Ages

18 to 43 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Infertile women aged 18 to 43,
Presenting one or 2 endometriotic cysts of 30 mm to 80 mm long axis, confirmed by ultrasound and/or pelvic MRI and without signs of atypia,
With indication of IVF/ICSI, first IVF/ICSI after the discovery of endometriosis cyst(s),
Having given their consent.

Exclusion criteria

A history of ovarian cystectomy,
A non-homogeneous cyst that cannot be punctured (risk of incomplete aspiration),
Complex adnexal image that cannot exclude an associated hematosalpinx (communicating hematosalpinx, tissue component),
A recent tubo-ovarian infection,
An active, untreated vaginal infection,
Anticoagulant treatment at a therapeutic dose,
All adult patients protected by law (under guardianship or curatorship),
Problems understanding the French language,
Participation in intervention research,
All patients not affiliated to the social security system.