Benefit of Roux-en-Y (R-Y) Reconstruction After Pancreaticoduodenectomy

Kochi University

Status: Unknown

Conditions: Pancreatic Cancer

Treatments: Procedure: R-Y reconstruction

Study type: Interventional

Funder types: Other

Identifiers

NCT00906802

RPD Study

Details and patient eligibility

About

One of the most common complications of pancreaticoduodenectomy (PD) is delayed gastric emptying (DGE), otherwise known as "gastroparesis," which is not fatal but results in prolonged hospital stay and increased hospital costs. Delayed gastric emptying is defined as nasogastric decompression after postoperative day (POD) 10 or a failure to tolerate a regular diet after POD 14. The incidence of DGE has been reported to range from 5% to 72%.

Full description

We hypothesized that the hand-sewn, two-layered, or continuous suture, could induce anastomotic edema to indeed the afferent peristalsis, which is one of the causes of DGE.

Enrollment: 40 estimated patients

Sex: All

Ages: 30 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• These patients were to undergo elective pancreatic head resection for the treatment of periampullary mass

Exclusion criteria

• A body weight loss greater than 10% during the six months prior to surgery
• The presence of distant metastases
• Seriously impaired function of vital organs due to respiratory, renal or heart disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

R-Y reconstruction

Experimental group

Description:

the reconstruction was performed by R-Y anastomosis

Treatment:

Procedure: R-Y reconstruction

conventional reconstruction

No Intervention group

Description:

the anastomosis was performed by B-II