Benefits of Breast MRI for Predicting of Histopathologic Cell Type of Small Breast Cancer

Mahidol University

Status and phase: Unknown; Phase 4

Conditions: Invasive Breast Cancer

Treatments: Radiation: MRI

Study type: Interventional

Funder types: Other

Identifiers

NCT01597999

15262

578/2533(EC4) (Other Identifier)

Details and patient eligibility

About

This study examines the additional benefits of magnetic resonance imaging (MRI) with Gadovist in early breast cancer with poor prognostic features.

Full description

Dedicated Contrast-enhanced Magnetic Resonance Imaging (DCE-MRI)

Enrollment: 60 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with invasive ductal carcinoma
• Patients undergoing DCE-MRI scan which are assessed according to BI-RADS lexicon
• Breast cancer patients with pathological diagnosed invasive ductal carcinoma with hormonal receptor (ER, PR and HER-2) response
• Patients who have signed on informed consent form Patients will undergo MRI imaging and the physicians will practice according to practice guidelines.

Exclusion criteria

• Patients under 18 years old or during pregnancy
• Patients with MRI's contraindications e.g. patients with cardiac pacemaker or are allergic to MRI contrast agent Patients with unstable clinical abnormality and might get unexpected clinical treatment

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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60 participants in 1 patient group

No treatment

Other group

Description:

Accuracy of magnetic resonance imaging (MRI) in predicting aggressiveness of early breast cancer according to molecular subtypes identified by ER PR and HER-2 status ( Additional benefits of magnetic resonance imaging (MRI) with Gadovist in early breast cancer with poor prognostic features )

Treatment:

Radiation: MRI