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Benefits of Total Intravenous Anesthesia Compared With Inhaled Anesthesia in Cardiovascular Surgery

C

Coordinación de Investigación en Salud, Mexico

Status

Unknown

Conditions

Cardiovascular Surgical Procedure

Treatments

Drug: Propofol
Drug: Sevoflurane

Study type

Observational

Funder types

Other

Identifiers

NCT03233815
R-2017-3604-95

Details and patient eligibility

About

This study compares the difference in proinflammatory markers Interleukin 6 (IL-6), Tumor necrosis factor alpha (TNFα) and cortisol in patients undergoing cardiovascular surgery to asses if there is a benefit of using intravenous total anesthesia (TIVA) over inhaled anesthesia for this procedures.

Full description

IL-6, TNFα and cortisol will be measure at the beginning of the cardiovascular surgery and 20 minutes after the cardiovascular bypass ends to calculate the difference between them and compare if there is any statistical difference between the proinflammatory markers with the two anesthesia techniques.

Enrollment

40 estimated patients

Sex

All

Ages

20 to 40 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Scheduled for cardiovascular surgery American Society of Anaesthesiologists (ASA) physical status classification II-IV BMI < 25 HbA1c < 7%

Exclusion criteria

Diabetic patients Known allergy to propofol

Trial design

40 participants in 2 patient groups

Inhaled anesthesia (Sevoflurane)
Description:
Patients undergoing cardiovascular surgery with inhaled anesthesia with sevoflurane.
Treatment:
Drug: Sevoflurane
Total Intravenous Anesthesia (Propofol)
Description:
Patients undergoing cardiovascular surgery with total intravenous anesthesia with propofol.
Treatment:
Drug: Propofol

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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