Berlin-Brandenburg Pregnancy Cohort (BBPC)

Charité University Medicine Berlin

Status: Enrolling

Conditions: Pregnancy Complications; Diabetes Mellitus in Pregnancy; Preeclampsia

Study type: Observational

Funder types: Other

Identifiers

NCT03313024

BBPC

Details and patient eligibility

About

This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.

Enrollment: 1,580 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy pregnant women after giving informed consent
• pregnant with diagnosis of preeclampsia, gestational hypertension or gestational diabetes

Exclusion criteria

• infections
• alcohol and drug abuse
• manifest and chronic diseases