Best Cutoff Value of Lactate Concentration in Vaginal Fluid to Predict Time of Spontaneous Onset of Labor in PPROM

Mennatallah Mohamed Elnemr

Status: Unknown

Conditions: Aim is to Investigate Association Between Lactate Concentration in Vaginal Fluid and Time of Spontaneous Onset of Labor in PPROM

Treatments: Diagnostic Test: Lactate concentration in vaginal fluid

Study type: Observational

Funder types: Other

Identifiers

NCT03463811

MElnemr

Details and patient eligibility

About

The present study is aimed to assess whether lactate determination in vaginal fluid is associated with and can predict onset of labor for women with suspected preterm prelabor rupture of membranes (PPROMs).

Full description

Study design: Prospective observational cohort

Enrollment: 42 estimated patients

Sex: Female

Ages: 25 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 25-35 years old
• BMI 25-30
• Singleton pregnancy in presentation with a history of suspected PPROM
• A live fetus with gestational age between 26+0 weeks and 34+0 weeks

Exclusion criteria

• Abruption placenta
• Medical disorders and hypertensive disorders of pregnancy
• Intrauterine fetal death
• Known or suspected fetal anomalies
• Signs of infection (Fever, increase total leucocytic count)
• Multiple pregnancy.
• Regular uterine contractions.
• History of cervical insufficiency