Beta Blocker Use in Cardiac Surgery and Association With Postoperative Course (BLOCK)

University Hospital Center (CHU) Dijon Bourgogne

Status: Completed

Conditions: Cardiac Surgery With Cardiopulmonary Bypass

Treatments: Other: collection of medical complications; Other: collection of the allocated treatment

Study type: Observational

Funder types: Other

Identifiers

NCT04769752

Guinot 2021

Details and patient eligibility

About

The objective of this study is to describe in a cohort of cardiac surgery patients the use of beta-blockers before surgery and their maintenance or withdraw according to international recommendations in order to compare patients who receive a beta-blocker with maintenance during the surgical period (international recommendation) to those for whom prescription and maintenance are not respected. Patients are treated according to standard practice and this protocol does not change patient management. No additional information or data is required by the study other than the data usually collected in the patient record (drug treatment, medical history, operating data, postoperative data, complications, length of stay).

The objectives of this research are :

• To evaluate the proportion of patients receiving beta-blocker treatment prior to cardiac surgery.
• To evaluate the proportion of patients receiving beta-blocker treatment before cardiac surgery and complying with international recommendations for its maintenance/stop in perioperative cardiac surgery.
• To evaluate the incidence of complications and length of hospital stay in patients receiving beta-blockers based on compliance or non-compliance with recommendations.

Enrollment: 1,789 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Major patient ≥ 18 years
• Patient operated cardiac surgery with cardiopulmonary bypass
• Patients who have given oral consent to participate after full information

Exclusion criteria

• Off pump cardiac surgery

Trial design

1,789 participants in 3 patient groups

No beta-blocker

Description:

Patient do no treat with beta-blocker before the surgery

Treatment:

Other: collection of the allocated treatment

Other: collection of medical complications

Beta blocker

Description:

Patient treat with beta-blocker in accordance to international guidelines

Treatment:

Other: collection of the allocated treatment

Other: collection of medical complications

Beta blocker2

Description:

Patient treat with beta-blocker without respect of international guidelines