BFR Training on Muscle Morphology

Udayana University

Status: Enrolling

Conditions: Anterior Cruciate Ligament Injuries; Blood Flow Restriction Training; Muscle Morphology; Patellofemoral Pain Syndrome; Eccentric Training

Treatments: Procedure: High load-Eccentric training; Procedure: Sham Low load-BFRt; Procedure: Low load-BFRt

Study type: Interventional

Funder types: Other

Identifiers

NCT06566950

1791/UN14.2.2.VII.14/LT.2024

Details and patient eligibility

About

This randomized clinical trial study compares high-load eccentric training (HL-Et), sham LL-BFRt, and low-load blood flow restriction (LL-BFRt) in sportsmen. The primary inquiries it seeks to address are:

Is LL-BFR superior to HL-Et and sham LL-BFRt in terms of improving muscle morphology? Is LL-BFR a more effective Patellofemoral Pain Syndrome and ACL injury preventive than HL-Et and sham LL-BFRt?

The three intervention groups that will be randomly assigned to participants are LL-BFRt, sham LL-BFRt, and HL-Et. Participants are expected to carry out:

Participants in LL-BFRt will be required to perform LL eccentric training at 30% of their repetition maximum (RM) and 70% of their artery occlusion pressure (AOP). This training will include stairs, single leg squat, and single leg deadlift.

Participants in HL-Et will be required to perform LL eccentric training at 70% of their maximum number of repetitions (RM).

In order to determine whether muscular morphology and the prevention of Patellofemoral Pain Syndrome and ACL injury improve following the interventions and follow-up, researchers will compare LL-BFRt, sham LL-BFRt, and HL-Et.

Enrollment: 75 estimated patients

Sex: All

Ages: 15 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Being between the ages of 15 and 35
• Play level 1 sports (fight martial arts, basketball, futsal, and soccer) at least twice a week
• Never experienced an Patellofemoral Pain Syndrome or ACL injury before
• Never experienced a grade III sprain or strain
• Consent to participate in the study until its conclusion and provide informed consent.

Exclusion criteria

• Having a tumor, cancer, vena thromboembolic disease, obesity, diabetes, hypertension, anemia, and renal failure
• Disabilities or those who are disabled.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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75 participants in 3 patient groups

Low load-BFRt

Experimental group

Description:

70% of the arterial occlusion pressure and 30% of the maximum repetition rate

Treatment:

Procedure: Low load-BFRt

Sham Low load-BFRt

Sham Comparator group

Description:

10% of the arterial occlusion pressure and 30% of the maximum repetition rate

Treatment:

Procedure: Sham Low load-BFRt

High load-Eccentric training

Active Comparator group

Description:

70% of the maximum repetition rate

Treatment:

Procedure: High load-Eccentric training