BHCG Level in Day 4,7, in Comparison to Day 10 as an Indicator for Treatment Success

Clalit Health Services

Status and phase: Unknown; Phase 4

Conditions: Ectopic Pregnancy

Treatments: Drug: Methotrexate

Study type: Interventional

Funder types: Other

Identifiers

NCT01860690

BHCG1

Details and patient eligibility

About

The investigators want to compeer BHCG levels after Methotrexate ( MTX). treatment for Ectopic pregnancy in days 4 and 7 after MTX. to day 10 . The hypothesis is that "BHCG" level in day 10 is the best indicator for treatment success , superior to day 4 and 7 . According to the investigators impression BHCG level rises in days 4 and 7 due to destruction of the trophoblast tissue , and only day 10 is an indicator for treatment success

Enrollment: 100 estimated patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients with ectopic pregnancy
• healthy
• hemodynamic stable
• first ectopic

Exclusion criteria

• hemodynamic non-stable
• abnormal liver or kidney function
• allergy reaction to MTX

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

100 participants in 1 patient group

MTX , treatment outcome

Experimental group

Description:

patient receiving MTX. in a dosage of 50 mg/m\^2 , IM , in single dose

Treatment:

Drug: Methotrexate