Bilateral Dual Transversus Abdominis Plane Block for Robotic Assisted Laparoscopic Surgery

Aalborg University Hospital

Status: Terminated

Conditions: Robotic Assisted Laparoscopic Surgery; Pain Treatment; Bilateral Dual Transversus Abdominis Plane Block

Treatments: Drug: Isotonic potassium chloride; Drug: Ropivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT01760161

20120042

Details and patient eligibility

About

To evaluate the effects of bilateral dual transversus abdominis plane block on postoperative pain after robotic assited laparoskopic surgery and measure the plasma-level of ropivacain after the bilateral dual transversus abdominis plane block.

Full description

After randomisation patients for robotic assisted laparoscopic surgery will receive bilateral dual transversus abdominis plane block containing either ropivacain or isotonic potassium chloride.

The investigators will record pain-score, opioid-consumption and sensibility on the abdominal wall in the postoperative periode.

Also a blood sample will be taken at 15, 30, 60, 120 and 240 minutes after the block in order to measure the plasma-level of ropivacain after bilateral dual transversus abdominis plane block.

The investigators assume that there will be significant effect on postoperative pain and that the level of plasma-ropivacain will be acceptable.

Enrollment: 80 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients scheduled for robotic assisted laparoscopis surgery
• acceptance to participate

Exclusion criteria

• allergies to local analgetics
• daily use of strong opioids

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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80 participants in 2 patient groups, including a placebo group

Ropivacain

Active Comparator group

Description:

Ropicacain 3,75 mg/ml 15 ml x 4 when placing the Bilateral Dual Transverus Abdominis Plane block

Treatment:

Drug: Ropivacaine

Isotonic potassium chloride

Placebo Comparator group

Description:

Isotonic potassium chloride 15 ml x 4 when placing the bilateral dual transverus abdominis plane block.

Treatment:

Drug: Isotonic potassium chloride