Bile Leak After Liver Surgery

University of Milan

Status: Completed

Conditions: Liver Resection; Hepatic Resection; Bile Leak; Hepatectomy; Biliary Fistula

Treatments: Procedure: Hepatic resection

Study type: Observational

Funder types: Other

Identifiers

NCT02056028

BileLeakLiverSurgery

Details and patient eligibility

About

The definition of biliary fistula is heterogeneous and the more accepted is that proposed by the ISGLS. We devised a precise definition of post-resectional biliary fistula and a well-established policy both for its disclosure and management.Aim was the validation of our definition, and management of biliary fistula after hepatic resection in a large prospective cohort of patients and its comparison with that of the International Study Group of Liver Surgery (ISGLS).

Full description

Data on abdominal drains and on clinical, pathological and short-term outcome were reviewed in a prospective cohort of patients who underwent hepatic resection between 2004 and 2012. Drains were maintained at least 7 days, and the bilirubin levels were measured in POD3, 5, and 7. Drains were removed if the bilirubin level in POD7 was inferior than in POD5, and less than 10 mg/dl. Statistical analysis on prognostic factors for biliary fistula was performed.

Enrollment: 475 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• any patient submitted to hepatic resection at our Unit between the established frame time

Exclusion criteria

• any patient with incomplete data or follow-up

Trial design

475 participants in 1 patient group

Bile leak after hepatic resection

Treatment:

Procedure: Hepatic resection