Bilirubin Levels to Diagnose Appendicitis and Predict Appendiceal Perforation

Nepalese Army Institute of Health Sciences

Status: Completed

Conditions: Appendicitis Perforated; Acute Appendicitis

Treatments: Other: Non-interventional

Study type: Observational

Funder types: Other

Identifiers

NCT06956638

IRB604

Details and patient eligibility

About

The goal of this study is to learn if serum bilirubin levels can aid in the diagnosis of acute appendicitis and predict appendiceal perforation

Full description

The study aims to assess hyperbilirubinemia: serum direct, indirect and total bilirubin to enhance the diagnostic accuracy of acute appendicitis. Also it aims to analyze different patient variables such as age, gender, duration of symptoms, leukocyte and neutrophil count, Alvarado score, presence of fever, nausea & vomiting, peritonitis alongside serum total bilirubin level in patients with appendicitis and assess which variables can be taken as independent factors to predict appendiceal perforation.

Enrollment: 98 patients

Sex: All

Ages: 5+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of age group above 5 years with acute appendicitis undergoing appendectomy with written informed consent.

Exclusion criteria

• Patients with appendicular lump.
• Patients with acute and chronic liver diseases like acute hepatitis, hemolytic disease, Gilbert's syndrome, Dubin-Johnson syndrome, alcoholic liver disease.
• Acquired or Congenital Biliary Disease.
• History of Hepatotoxic drugs.

Trial design

98 participants in 1 patient group

Patients of age group above 5 years with acute appendicitis undergoing appendectomy

Description:

Patients of age group above 5 years with acute appendicitis undergoing appendectomy, without acute or chronic liver diseases, acquired or congenital bilirary diseases, history of use of hepatotoxic drugs or diagnosis of appendicular lump

Treatment:

Other: Non-interventional