Bio-Repository of High Risk Cohorts for the Early Detection of Pancreas Cancer

Stanford University

Status: Enrolling

Conditions: Pancreas Disease; Pancreatic Cyst

Treatments: Diagnostic Test: Bio-Specimen Collection

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT03260842

IRB-19286

Details and patient eligibility

About

Bio-repository to collect bio-specimens from patients with 1) pancreatic cysts and 2) patients at high risk, defined by family history and/or genetic mutations, for pancreatic cancer.

Full description

Observational study to collect bio-specimens from 2 separate patient cohorts identified to be at high risk for subsequent development of pancreas cancer.

1. Patients diagnosed with a pancreatic cyst undergoing either endoscopic ultrasound or surgery. Bio-specimens collected include pancreatic cyst fluid and blood. These will be collected using a standard operating protocol.
2. Patients defined as a high risk individual for pancreas cancer by family history and/or known genetic mutations. Bio-specimens collected include blood. This will be collected using a standard operating protocol.

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Older than 18 with pancreas cyst
• Older than 18 at high risk for Pancreas cancer

Exclusion criteria

• Unable to provide consent
• Not willing to provide bio-specimens

Trial design

500 participants in 2 patient groups

Pancreatic Cysts

Description:

Patients with pancreatic cyst undergoing endoscopic ultrasound and/or surgery who will have bio-specimens collected

Treatment:

Diagnostic Test: Bio-Specimen Collection

High Risk Individuals

Description:

Patients with established family history and/or genetic mutations for Pancreas cancer who will have bio-specimens collected

Treatment:

Diagnostic Test: Bio-Specimen Collection