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Bioactive Glass in the Treatment of Enamel White Spot Lesions

R

Rania Salah

Status and phase

Completed
Phase 3

Conditions

White Spot Lesion of Tooth

Treatments

Drug: Novamin
Drug: CPP-ACP
Drug: BiominF

Study type

Interventional

Funder types

Other

Identifiers

NCT04401280
WSL treatment

Details and patient eligibility

About

the aim of this study is to evaluate the effectiveness of BiominF® and Novamin® in comparison to Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) in the treatment of enamel white spot lesions

Enrollment

60 patients

Sex

All

Ages

14 to 26 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Not less than 1 white spot lesion on the labial surface of teeth in the anterior region with code 2 International Caries Detection and Assessment System II (ICDAS-II) or less
  • Absence of any active periodontal disease.
  • Written informed consent

Exclusion criteria

  • Known hypersensitivity/allergy to study products and/or materials used
  • teeth having deep carious lesions or extensive restorations
  • Unwillingness to be randomly assigned to 1 of the 3 treatment groups
  • Advanced periodontal disease.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

60 participants in 3 patient groups

BiominF®
Active Comparator group
Description:
Test group
Treatment:
Drug: BiominF
Novamin®
Active Comparator group
Description:
Test group
Treatment:
Drug: Novamin
CPP-ACP
Active Comparator group
Description:
Control group
Treatment:
Drug: CPP-ACP

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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