Bioavailability of Anthocyanins of Blue Potatoes as Compared With Bilberries

University of Turku

Status: Completed

Conditions: Postprandial Glycemia

Treatments: Other: Dietary intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT02005796

Siniset perunat

Details and patient eligibility

About

In this study, the postprandial glycemia and insulinemia caused by boiled potato with blue-fleshed or yellow-fleshed tubers, or a gel prepared with bilberries and potato starch, is studied in healthy males. Additionally, the appearance and metabolism of the flavonoids and their metabolites is studied in plasma and urine.

Enrollment: 14 patients

Sex: Male

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18-45
• Male
• No regular medication
• No participation in a drug trial or blood donation within 2 months
• Non-smoker
• Signs informed consent
• Body mass index 18.5-27 kg/m2
• Fasting plasma cholesterol < 5.5 mmol/l
• Fasting plasma triacylglycerols < 2.6 mmol/l
• Fasting plasma glucose 4-6 mmol/l
• blood pressure <140/80 mmHg
• hemoglobin>130 g/l
• Fasting plasma alanine amino transferase (ALAT) <60 U/l (normal liver function)
• Fasting plasma thyroid-stimulating hormone (TSH) 0.4 - 4.5 mU/l (normal thyroid function)
• Fasting plasma creatinine <118 µmol/l (normal kidney function)

Exclusion criteria

• Regular smoking
• Alcohol abuse
• Regular medication

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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14 participants in 3 patient groups

Blue-fleshed potato tubers

Experimental group

Description:

Intervention: Steam cooked mashed potato tubers

Treatment:

Other: Dietary intervention

Yellow-fleshed potato tubers

Experimental group

Description:

Intervention: Steam cooked mashed potato tubers

Treatment:

Other: Dietary intervention

Bilberries and potato starch

Experimental group

Description:

Intervention: A gel boiled with bilberries and potato starch

Treatment:

Other: Dietary intervention