Biobank for African American Prostate Cancer Research in Florida

H. Lee Moffitt Cancer Center and Research Institute

Status: Completed

Conditions: Prostate Cancer

Treatments: Other: Saliva Samples; Other: Tumor Tissue; Other: Questionnaires

Study type: Observational

Funder types: Other

Identifiers

NCT03232411

MCC-18643

Details and patient eligibility

About

The purposes of this study are: a) to develop a statewide Biobank for prostate cancer among men of African Ancestry in Florida and; b) to examine whether smoking increases the aggressiveness of prostate cancer using several biological approaches.

Investigators plan to contact African American prostate cancer patients regarding participation. This project has 3 main components. Eligible patients may choose to participate in any or all parts of the study: Questionnaires; Saliva Samples; Tumor Tissue.

Full description

This project will create the first state-wide data and biospecimen bank for men of African ancestry with prostate cancer. The sampling strategy and size of the study population ensure that the cohorts is representative, enhancing validity of studies based on this resource. In addition, there are no data on the role of smoking in African American prostate cancer. The approach to share the resource with Florida prostate cancer researchers is innovative and possible because the four annual prostate cancer symposiums organized by Moffitt has unified many Florida prostate cancer researchers who are now well connected and actively collaborating, as evidenced by publications and funded projects among participants.

Enrollment: 592 patients

Sex: Male

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The initial recruitment of cases will be done with 3 mailings: the first to introduce the study to the participant from Florida Cancer Data System (FCDS) of the Florida Department of Health and ask them to complete the eligibility form and contact information update form; a second mailing to those who are determined to be eligible for the study to obtain the Informed Consent Form and the Baseline survey; and a third mailing to those who completed the survey to obtain a saliva sample and medical release form for tissue.
• Histologically biopsy confirmed, primary prostate cancer, diagnosed between January 2013 and December 2015
• African American or Black; Hispanic Black; Afro-Caribbean
• Are at least 20 years old
• Are a resident of Florida
• Additional criteria may apply

Exclusion criteria

• Does not meet Inclusion Criteria