Biobanking and New Biomolecular Metrics (Melamoma4p)

Regina Elena Cancer Institute

Status: Enrolling

Conditions: Melanoma (Skin); Liquid Biopsy

Treatments: Diagnostic Test: Biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT05906277

RS1174/19

Details and patient eligibility

About

The goal of this Interventional study aims to apply, in our Institutes, a 4p oncological model i.e. predictive, personalized, of precision and participated (Regina Elena and San Gallicano).

Full description

Patients will be recruited with an innovative and systematic scheme: collection and biobanking of biological materials (tissue biopsy, re-biopsy and liquid biopsy) followed by a molecular monitoring thanks to genomic and epigenomic methods. It's an open-ended study. In particular we will try to identify new "actionable" signatures and we will try to insert the patients to innovative clinical trials, thanks to the evaluation of all cases with a Molecular Tumor Board.

The main objectives are:

• Introduce a new methodology to improve and integrate the already existent institutional PDTA
• Evaluate and measure the applicative value
• Establish a biostatistical platform

Enrollment: 300 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Melanoma affected patients

Exclusion criteria

• No patiens affected by other pathology

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Sequential Assignment

Masking: None (Open label)