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Biodiversity Interventions for Assisted Living Centers (BIWE)

N

Natural Resources Institute Finland

Status

Active, not recruiting

Conditions

Autism Spectrum Disorder
Immune System and Related Disorders
Microbial Colonization
Nature, Human
Visual Impairment
Well-Being, Psychological

Treatments

Other: Rewilding

Study type

Interventional

Funder types

Other

Identifiers

NCT06390683
HUS/11940/2022

Details and patient eligibility

About

Biodiversity is essential for nature and human well-being. Land use has reduced biodiversity in cities, which weakens the functionality of the urban ecosystems and the well-being of citizens. This may also increase the risk of immune-mediated disorders among urban dwellers.

In Biodiversity interventions for assisted living centers (BIWE 2), microbial biodiversity interventions are performed to increase biodiversity in urban housing units for people with autism spectrum disorder, disabled people and elderly. Results from the intervention trials are combined with publicly available land cover and ecological data. These are analyzed from the viewpoint of shifts in ecosystems and human well-being and immune regulation, ecological quality, and urban planning.

The investigators set up an intervention study in which yards of the housing units are rewilded with diverse vegetation and decaying deadwood and plant residuals. The investigators aim to evaluate the effect of rewilding, and yard management practices on commensal microbiome, cortisol levels and well-being and salivary cytokine levels, and gene pathways.

Full description

Our specific aims are:

To assess if rewilding diversifies health-associated skin microbiota and is associated with salivary cytokine levels, gene pathways, cortisol levels and commensal microbiota.

Assess whether there are patterns in the microbiome associated with the salivary cytokine levels and hair cortisol levels.

Assess whether rewilding affects health and psychological measures. The investigators will recruit approximately 36 study subjects living in assisted housing units in urban areas and aged between 18-82.

Enrollment

36 estimated patients

Sex

All

Ages

18 to 82 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Person lives in assisted living center

Exclusion criteria

  • Immunosuppressive medications
  • Immune deficiencies
  • a disease affecting immune response (colitis ulcerosa, rheumatoid arthritis, Crohn's disease, diabetes)
  • cancer diagnosis within the last year or on-going cancer treatment

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

36 participants in 1 patient group

Rewilding
Experimental group
Description:
Yards of the housing units are rewilded with vegetation, deadwood and plant residuals.
Treatment:
Other: Rewilding

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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