Biofilms on Short-term Indwelling Ureteral Stents

Cantonal Hospital of St. Gallen

Status: Completed

Conditions: Ureteral Catheterization; Biofilm; Morbidity

Treatments: Other: Stent examination, urinary analysis, USSQ questionnaire

Study type: Observational

Funder types: Other

Identifiers

NCT02845726

CTU 15.010

Details and patient eligibility

About

This study is performed to analyze various aspects of biofilms on ureteral stents.

Full description

The study is performed to provide a better understanding of the influence of biofilms on ureteral stents on the entire spectrum of stent-associated morbidity.

Moreover, it could provide more detailed knowledge about the correlation of the occurrence of biofilms on ureteral stents and findings in urinary analysis, which could serve as a decision support whether patients with ureteral stents undergoing further interventions (for example ESWL or simple secondary URS) should receive antibiotic prophylaxis.

Correlation of results of urinary bacteriologies (assessed pre- and intraoperatively) and biofilm analysis on stents could provide information if "targeted antibiotic treatment" based on urinary bacteriology only is possible at all.

Correlation of urinary analysis and conventional urinary bacteriology could provide a valuable contribution regarding the prediction of bacteriuria and the necessity of postponing operations.

Additionally, the study is intended to provide an overview over the recent bacterial species that are involved into biofilms on ureteral stents and their resistance to antibiotics. This could provide valuable information about the choice of antibiotics in cases were treatment has to be performed empirically.

Enrollment: 85 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients temporarily undergoing ureteral stenting
• Informed consent

Exclusion criteria

• Bilateral stenting
• Ureteral obstruction due to malignancies
• Additionally performed procedures/operations during stent indwelling time -Cognitively impaired patients
• UTI at the time of stent insertion (>10 to the power of 2 cfu/ml)

Trial design

85 participants in 1 patient group

Patients with temporary ureteral stent

Description:

Assessment of patients transiently undergoing ureteral stenting.

Treatment:

Other: Stent examination, urinary analysis, USSQ questionnaire