Biological Markers for the Diagnosis of Central Nervous System Infective Diseases

Air Force Military Medical University of People's Liberation Army

Status: Unknown

Conditions: Infection

Study type: Observational

Funder types: Other

Identifiers

NCT02278016

xijing-120

Details and patient eligibility

About

Bacterial meningitis is a potentially life-threatening disease that is associated with substantial neurological morbidity and mortality. Accurate diagnosis is essential to improve outcome and prevent antibiotic overuse. Here we try to explore new biological markers for the diagnosis of the central nervous system infection disease.

Full description

To investigate the diagnosis value of procalcitonin,interleukin-6, agiotensininⅡin the cerebrospinal fluid in the central nervous system infection disease.

Enrollment: 150 estimated patients

Sex: All

Ages: 13+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Aged 13 years or older;
2. At least two of the following clinical characteristics:headache, fever, neck stiffness, mental symptoms or consciousness impairment or seizures
3. Patients' family signed informed consent.

Exclusion criteria

1. Contraindications to lumbar puncture
2. Patients with active malignancy