Biological Variability in Cartilage Specific Biomarkers in Healthy Volunteers. (COVAR)

Artialis

Status: Completed

Conditions: Urine Marking; Effects of; Serum

Treatments: Other: serum and urine sample

Study type: Observational

Funder types: Industry

Identifiers

NCT02348944

COVAR

Details and patient eligibility

About

The purposes of the study are to assess intra individual biological variability of serum and urinary cartilage specific biomarkers and define the best standardized conditions for blood and urine sampling in the frame of biomarkers dosage.

Full description

To assess intra individual biological variability of serum and urinary cartilage specific biomarkers and define the best standardized conditions for blood and urine sampling in the frame of biomarkers dosage. Variation factors assessed are:

• Fasting condition
• Sampling time
• Sampling season
• Physical activity
• Duration and temperature of total blood treatment
• Type of blood collection tube.

Enrollment: 15 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or female, aged above 18 years.
• Sign an informed consent after being informed
• Able to follow the instructions of the study

Exclusion criteria

• Serious associated diseases:

  • Severe liver disease
  • Renal failure
  • HIV
  • hepatitis B or C

• Patient who are the subject of a judicial protection measure or under guardianship

Trial design

15 participants in 1 patient group

15 healthy volunteers

Description:

Other: serum and urine sample

Treatment:

Other: serum and urine sample