Biomagnetic Signals of Intestinal Ischemia

University of South Alabama (USA)

Status: Completed

Conditions: Ischemia

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00285545

R01DK058197 (U.S. NIH Grant/Contract)

DK58197

Details and patient eligibility

About

The lack of blood flow to the small intestine causes mesenteric ischemia. Using a Superconducting QUantum Interference Device (SQUID) which measures the magnetic field of the small intestine, we are hoping to identify abnormalities without surgical intervention.

Full description

The electrical activity of the small intestine may contain important information that will help us diagnose gastrointestinal diseases. The major impediment to reducing mortality of mesenteric ischemia is the lack of a noninvasive diagnostic test that identifies the syndrome before extensive necrosis occurs. Mesenteric ischemia is caused by the lack of blood flow to the intestine. The Superconducting QUantum Interference Device (SQUID) measures the magnetic field of the intestinal smooth muscle. By comparing normal smooth muscle and that of patients with mesenteric ischemia, we hope to identify abnormal disease states without surgery.

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal Subjects and those diagnosed with mesenteric ischemia

Exclusion criteria

• Subjects who report a tendency toward claustrophobia

Trial design

60 participants in 2 patient groups

Good blood flow

Description:

Group with normal blood flow to small intestine

Poor blood flow

Description:

Group with partial ischemia to small intestine