Biomarker for Rapid Diagnosis of Hemispheric Stroke (BE FAST!)

Johann Wolfgang Goethe University Hospital

Status: Completed

Conditions: Acute Stroke

Study type: Observational

Funder types: Other

Identifiers

NCT00916864

BEFAST!-1

Details and patient eligibility

About

The aim of the study is to estimate the diagnostic accuracy of a combined biomarker test (including NMDA-Receptor fragments [NR2-peptide] and Glial fibrillary acidic protein) used to differentiate between cerebral ischemia and intracerebral hemorrhage in patients with acute hemispheric stroke.

Enrollment: 250 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• hemiparesis
• at least one sign of cortical involvement (e.g., aphasia, neglect, gaze deviation, reduced level of consciousness)
• hospital admission within 4.5 hours after symptom onset

Exclusion criteria

• stroke/TIA within the last 3 months
• traumatic brain injury within the last 3 months
• history of brain tumor