Biomarker-s of Abusive Head Trauma by Proteomics

University Hospitals (UH)

Status: Not yet enrolling

Conditions: Protein Disorder, Blood; Abuse, Child

Treatments: Other: Blood test

Study type: Observational

Funder types: Other

Identifiers

NCT05626465

2021-01971

Details and patient eligibility

About

The aim of our study is to highlight biomarker-s of Abusive Head Trauma by proteomics analyses on the serum of child victims of abuse.

Enrollment: 174 estimated patients

Sex: All

Ages: Under 2 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age : 0-2 y.o
• Medical consultation for malaise, seizure (without fever), loss of consciousness, traumatic bain injury, or cranioplasty
• Blood test during medical care
• Accepted informed consent

Exclusion criteria

• Refused informed consent
• For control groups : medical history of child abuse
• For AHT group : rare metabolic disease (Menkes, etc..)

Trial design

174 participants in 4 patient groups

Abusive Head Trauma (AHT)

Treatment:

Other: Blood test

Accidental traumatic brain injury

Treatment:

Other: Blood test

Cranioplasty

Treatment:

Other: Blood test

Infant malaise without AHT

Treatment:

Other: Blood test