Biomarker Study in Samples From Patients With Malignant Rhabdoid Tumor of the Kidney or Atypical Teratoid Rhabdoid Tumor

Children's Oncology Group

Status: Withdrawn

Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor; Rhabdoid Tumor of the Kidney

Treatments: Other: Laboratory Biomarker Analysis

Study type: Observational

Funder types: NETWORK; NIH

Identifiers

NCT01453465

NCI-2011-03468 (Registry Identifier)

CDR0000712872

ABTR12B1

COG-ABTR12B1

Details and patient eligibility

About

This research trial studies biomarkers in samples from patients with rhabdoid tumor of the kidney and atypical teratoid rhabdoid tumor. Studying biomarkers of tissue samples from patients with cancer in the laboratory may help doctors learn more about changes the occur in DNA and identify biomarkers related to cancer.

Full description

PRIMARY OBJECTIVES:

I. To determine if there are molecular differences between rhabdoid tumor of the kidney (RTK) and the atypical teratoid rhabdoid tumor (ATRT).

OUTLINE:

Archived tumor tissue samples are analyzed for gene expression profile and microRNA profile.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Samples of RTK and ATRT provided by the Children?s Oncology Group (COG)

Trial design

0 participants in 1 patient group

Ancillary-Correlative (gene expression profile, miRNA profile)

Description:

Archived tumor tissue samples are analyzed for gene expression profile and microRNA profile.

Treatment:

Other: Laboratory Biomarker Analysis