Biomarkers for Bipolar Disorder: Chaperones and Reticulum Endoplasmatic Stress Response CHAP´s Study (CHAPS)

University of Sao Paulo

Status: Suspended

Conditions: Bipolar Disease Type I

Study type: Observational

Funder types: Other

Identifiers

NCT00994630

CHAPS STUDY

Details and patient eligibility

About

The purpose of this study is to determine expression of chaperones proteins from the endoplasmatic reticulum stress response system in bipolar I patients (manic phase) compared to healthy controls.

Hypothesis: There is no difference in chaperones proteins expression between bipolar I manic patients and healthy controls

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Bipolar Disease type I manic phase
• YMRS > 14
• HDRS < 9

Exclusion criteria

• Use of lithium, divalproate, or carbamazepine in therapeutic levels over the past 30 days

Trial design

20 participants in 1 patient group

BP I patients manic phase