Biomarkers of Chronic Obstructive Pulmonary Disease (BIOBPCO)

Centre Hospitalier Universitaire, Amiens

Status: Completed

Conditions: Asthma-COPD Overlap Syndrome; Asthma; COPD

Treatments: Diagnostic Test: blood test; Other: Physical examinations

Study type: Observational

Funder types: Other

Identifiers

NCT04963023

PI2021_843_0051

Details and patient eligibility

About

There are few studies about immunological explorations in COPD. Because of the complications of lung biopsies, analyses are generally made on blood samples instead of lung tissue. No study tried to classify COPD vs Asthma vs ACOS. The investigators wondered if there were differences in biomarkers between these groups. The investigators decided to open a pilot-study among COPD patients followed in Amiens-University Hospital. Each patient will be examined and a blood-test will be performed.

Enrollment: 75 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BPCO patients
• ACOS patients
• asthmatic patient without BPCO

Exclusion criteria

• infection
• exacerbation
• immunosuppressive treatment
• immunosuppressive disease

Trial design

75 participants in 4 patient groups

frequent exacerbation patients

Treatment:

Diagnostic Test: blood test

Other: Physical examinations

non frequent exacerbation patients

Treatment:

Diagnostic Test: blood test

Other: Physical examinations

Asthma-and-COPD overlap syndrome

Treatment:

Diagnostic Test: blood test

Other: Physical examinations

Asthmatic patients (without COPD)

Treatment:

Diagnostic Test: blood test

Other: Physical examinations