National Multicenter Cohort Registry Study of Rapid rEcurrences of Coronary Unexplained In-stent Restenosis (RECUR Registry)

National Center for Cardiovascular Diseases

Status: Enrolling

Conditions: Arteritis; Coronary Artery Disease; In-Stent Stenosis (Restenosis) of Coronary Artery Stent

Treatments: Other: Treatment made by experienced clinicians

Study type: Observational

Funder types: Other

Identifiers

NCT05437965

2021-ZX50

Details and patient eligibility

About

This project aims to establish a clinical cohort and diagnostic assessment framework by conducting a national multicenter cohort registry study. Through the collection of patients' clinical characteristics, it will achieve the registration, management, follow-up, and analysis of patients with Rapid rEcurrences of Coronary Unexplained in-stent Restenosis (RECUR).

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age ≥ 18 years;
2. Patients meeting the diagnostic criteria for Rapid rEcurrences of Coronary Unexplained in-stent Restenosis (RECUR);
3. Patients fully informed about the trial procedures who provide written informed consent.

Exclusion criteria

1. Patients presenting with any of the following:

   • Other severe comorbidities (e.g., malignant tumors, heart failure) with a life expectancy <12 months;

     • Known autoimmune/rheumatic diseases including systemic lupus erythematosus, Takayasu arteritis, Behçet's disease, polyarteritis nodosa, Wegener granulomatosis (granulomatosis with polyangiitis), eosinophilic arteritis, giant cell arteritis, rheumatoid arthritis, or IgG4-related disease;

       • Variant angina (Prinzmetal's angina);

         • Coronary artery dissection;

           • Thrombophilia;

             • Stent underexpansion.

2. Presence of psychiatric disorders;

3. Known inability to complete expected study follow-up for any reason;

4. Patients deemed ineligible for enrollment by the investigator.

Trial design

1,000 participants in 1 patient group

Rapid rEcurrences of Coronary Unexplained in-stent Restenosis (RECUR)

Treatment:

Other: Treatment made by experienced clinicians