Biomechanical Changes After Trabeculectomy (TE-biomech)

Technische Universität Dresden

Status: Completed

Conditions: Glaucoma, Primary

Treatments: Procedure: trabeculectomy

Study type: Observational

Funder types: Other

Identifiers

NCT02287545

EK399122012

Details and patient eligibility

About

Corneal biomechanics are studied in glaucoma patients prior and at least 6 month after trabeculectomy.

Full description

Prior to trabeculectomy corneal biomechanics are measured with the Ocular Response Analyzer (ORA, Reichert) and the Corvis st (Oculus). Both instruments work with an air-puff which deforms the cornea. Intraocular pressure is measured like in non-contact air-puff tonometry. The ORA also measures corneal hysteresis (CH) and the corneal resistance factor (CRF) which are qualitative measures of corneal biomechanics. The Corvis is a high-speed Scheimpflug-camera (4330 frames/sec) that records the quantitative movements of the cornea. At least 6 month after uncomplicated trabeculectomy the measurements are repeated.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Glaucoma patients in need of further IOP-reduction despite maximally tolerated therapy and assigned for trabeculectomy. Minimum of 18 years.

Exclusion criteria

• Corneal pathologies.

Trial design

30 participants in 1 patient group

Glaucoma, primary

Description:

Glaucoma patients undergoing trabeculectomy

Treatment:

Procedure: trabeculectomy