Biomechanical Parameters of Gait in Patients With Parkinson's Disease and Parkinsonian Syndromes

Groupe Hospitalier Pitie-Salpetriere

Status: Terminated

Conditions: Gait Disorders, Neurologic

Treatments: Device: Force platform and electromyography

Study type: Interventional

Funder types: Other

Identifiers

NCT00139321

RBM0260

Details and patient eligibility

About

Gait disorders and falls are frequent in patients with parkinsonian syndromes. In patients with Parkinson's disease (PD), these signs occurred later during the course of the disease in comparison to patients with other degenerative parkinsonian disorders. The pathophysiology of these symptoms are still not fully understood. Gait initiation challenges the balance control system as the body moves from an upright stable static posture to a continuously unstable gait. The aim of this study is to analyse the gait initiation process in patients with parkinsonian disorders.

Enrollment: 110 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients able to walk without assistance
• Patients with Parkinson's disease or other degenerative parkinsonian syndromes (progressive supranuclear palsy [PSP], multiple system atrophy [MSA], corticobasal degeneration [CBD], etc.)

Exclusion criteria

• Other parkinsonian syndromes
• Dementia
• Neuroleptic treatment

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)